I had kudgel issues, he never attacked after talking to the good Dr. I saw someone else post to throw grenades. I killed him with stink pot even though it appeared as if nothing was happening. You will see the red stats if you are doing damage.
I had the same frustrations as you, and all of the same errors. I am running Windows 10 with DirectX 12. I finally got it working by uninstalling TLOPO, and the files I had copied manually. Then I rebooted. Then I ran the DirectX install found at...